Observations in scopolamine-morphine-chloroform narcosis.
Vrachebnaya Gazeta (Saint-Petersburg). 1911;31:126-128.
In a series of 80 patients, Dr. Grigoryan from Tiflis [currently Tbilisi] Mikhaylovskaya Hospital studied the use of scopolamine-morphine injections before chloroform narcosis. As a result, the author concluded that the technique is safe, and the patients had less worrisome preoperative stage, less agitation, less vomiting, and less postoperative headache. The results represent an example of a patient-centered approach utilized in the beginning of 20th century.